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General characteristics of clinical observations of acute pancreatitis of biliary etiolog

https://doi.org/10.51922/1818-426X.2023.2.24

Abstract

The dynamics of hospital morbidity and lethality rate in acute biliary pancreatitis are analyzed; demographic regularities of acute biliary pancreatitis morbidity are determined; general characteristics of clinical observations are presented.

The increase in the absolute number of patients with acute pancreatitis of biliary etiology and necrotic pancreatitis of biliary etiology in many respects determines the growth of acute pancreatitis morbidity in general.

The morbidity of acute pancreatitis of biliary etiology is almost evenly distributed between men and women with the ratio 1,4:1. The peak of morbidity (36,1 %) falls on elderly age. In the age structure of acute biliary pancreatitis the share of elderly and senile age was 62,6 %. Every third patient sought medical help during the first 12 hours, 64,4 % – during the first 24 hours, 78,1 % – during the first 48 hours of the disease onset. The category of patients with the highest proportion (14,2 %) were elderly men, who came for treatment in the first 24 hours after the onset of the disease.

In 82,7 % of patients with acute biliary pancreatitis the premorbid status was aggravated by two or more concomitant diseases, every 5th patient had CHD manifested by angina pectoris, postinfarction cardiosclerosis or rhythm disturbances. Premorbid status has a significant influence on the overall mortality in acute pancreatitis of biliary etiology.

The relapses of acute pancreatitis of biliary etiology make up 9,6 % of all the attacks of the disease and 25,3 % of all relapses of acute pancreatitis, and in 47,6 % of cases of recurrent acute pancreatitis of biliary etiology the disease has an equally or more severe course with possible lethal outcome.

About the Authors

A. V. Mazanik
ГУ «432 ордена Красной Звезды главный военный клинический медицинский центр Вооруженных Сил Республики Беларусь»
Belarus


N. Yu. Blakhov
ГУ «432 ордена Красной Звезды главный военный клинический медицинский центр Вооруженных Сил Республики Беларусь»
Belarus


O. A. Chumanevich
ГУ «432 ордена Красной Звезды главный военный клинический медицинский центр Вооруженных Сил Республики Беларусь»
Belarus


S. L. Karvash
ГУ «432 ордена Красной Звезды главный военный клинический медицинский центр Вооруженных Сил Республики Беларусь»
Belarus


D. I. Patsai
ГУ «432 ордена Красной Звезды главный военный клинический медицинский центр Вооруженных Сил Республики Беларусь»
Belarus


A. P. Trukhan
ГУ «432 ордена Красной Звезды главный военный клинический медицинский центр Вооруженных Сил Республики Беларусь»
Belarus


References

1. Bagnenko, S. F. Hirurgicheskaya pankreatologiya / S. F. Bagnenko, A. A. Kurygin, G. I. Sinenchenko. – SPb.: Rech’, 2009. – 798 s.: il.

2. Paskar’, S. V. Patogeneticheskie podhody v lechenii biliarnogo pankreatita / S. V. Paskar’ // Vestn. Ros. Voen.-med. akad. – 2010. – T. 3, № 31. – S. 78–83.

3. Savel’ev, V. S. Ostryj pankreatit / V. S. Savel’ev, M. I. Filimonov, S. Z. Burnevich // Klinicheskaya hirurgiya: nacional’noe rukovodstvo: v 3 t. / pod red. V. S. Savel’eva, A. I. Kirienko. – M.: GEOTAR-Media, 2009. – T. 2. – S. 196–228.

4. Sovremennye predstavleniya o patogeneze, diagnostike i hirurgicheskom lechenii biliarnogo pankreatita / S. Ya. Ivanusa [et al.] // Vestn. hirurgii im. I. I. Grekova. – 2017. – T. 176, № 1. – S. 120–124.

5. Acute Pancreatitis in Five European Countries: Etiology and Mortality / L. Gullo [et al.] // Pancreas. – 2002. – Vol. 24, № 3. – P. 223–7.

6. An Update on Recurrent Acute Pancreatitis: Data From Five European Countries / L. Gullo [et al.] // Am. J. Gastroenterol. – 2002. – Vol. 97, № 8. – P. 1959–62.

7. Analysis of Factors Associated with the Severity of Acute Pancreatitis according to Etiology / D. B Kim [et al.] // Gastroenterol. Res. Practi. – 2017. – Vol. 2017. – P. 1219464.

8. Cho, J. H. Comparison of clinical course and outcome of acute pancreatitis according to the two main etiologies: alcohol and gallstone / J. H. Cho, T. N. Kim, S. B. Kim // BMC Gastroenterol. – 2015. – Vol. 15. – P. 87.

9. Classification of acute pancreatitis – 2012: revision of the Atlanta classification and definitions by international consensus / P. A. Banks [et al.] // Gut. – 2013. – Vol. 62. – P. 102–111.

10. Comparative study of the outcome between alcohol and gallstone pancreatitis in a high-volume tertiary care center / J. Samanta [et al.] // JGH Open. – 2019. – Vol. 3. – P. 338–343.

11. Early endoscopic retrograde cholangiopancreatography in predicted severe acute biliary pancreatitis: a prospective multicenter study / H. C. van Santvoort [et al.] // Ann. Surg. – 2009. – Vol. 250, № 1. – P. 68–75.

12. Gallstone Pancreatitis in Older Patients: Are We Operating Enough? / M. D. Trust [et al.] // Surgery. – 2011. – Vol. 150, № 3. – P. 515–525.

13. Gallstone Pancreatitis: A Review / D. Cucher [et al.] // Surg. Clin. N. Am. – 2014. – Vol. 94. – P. 257–280.

14. Hu, C. Treatment strategy for gallstone pancreatitis and the timing of cholecystectomy / C. Hu, S.-Q. Shen, Z.-B. Chen // World J. Meta-Anal. – 2014. – Vol. 2, № 2. – P. 42–48.

15. Long-term Effectiveness of Cholecystectomy and Endoscopic Sphincterotomy in the Management of Gallstone Pancreatitis / A. Mustafa [et al.] // Surg. Endosc. – 2014. – Vol. 28, № 1. – P. 127–33.

16. Lowenfels, A. B. The changing character of acute pancreatitis: epidemiology, etiology, and prognosis / A. B. Lowenfels, P. Maisonneuve, T. Sullivan // Curr. Gastroenterol. Rep. – 2009. – Vol. 11, № 2. – P. 97–103.

17. Management Guidelines for Gallstone Pancreatitis. Are the Targets Achievable? / P. Sanjay [et al.] // JOP. – 2009. – Vol. 10, № 1. – P. 43–47.

18. Outcomes of early versus delayed cholecystectomy in patients with mild to moderate acute biliary pancreatitis: A randomized prospective study / S. L. Jee [et al.] // Asian J. Surg. – 2018. – Vol. 41, № 1. – P. 47–54.

19. Recurrence of Acute Gallstone Pancreatitis and Relationship With Cholecystectomy or Endoscopic Sphincterotomy / V. Hernandez [et al.] // Am. J. Gastroenterol. – 2004. – Vol. 99, № 12. – P. 2417–23.

20. Recurrent Biliary Acute Pancreatitis Is Frequent in a Real-World Setting / S. Stigliano [et al.] // Dig. Liver Dis. – 2018. – Vol. 50, № 3. – P. 277–282.

21. Shafi, A. A. Gallstone pancreatitis management: Are we following the guidelines? / A. A. Shafi, G. Al Saied, B. N. Al Harthi // Saudi J. Health Sci. – 2016. – Vol. 5, № 1. – P. 15–19.

22. The incidence and aetiology of acute pancreatitis across Europe / S. E. Roberts [et al.] // Pancreatology. – 2017. – Vol. 17, № 2. – P. 155–165.


Review

For citations:


Mazanik A.V., Blakhov N.Yu., Chumanevich O.A., Karvash S.L., Patsai D.I., Trukhan A.P. General characteristics of clinical observations of acute pancreatitis of biliary etiolog. Medical Journal. 2023;(2):24-30. (In Russ.) https://doi.org/10.51922/1818-426X.2023.2.24

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ISSN 1818-426X (Print)