FORMATION OF A FOLLOW-UP GROUP FOR ADOLESCENT GIRLS AT RISK OF DEVELOPING POLYCYSTIC OVARY SYNDROME

Abstract

Polycystic ovary syndrome (PCOS) is one of the most common endocrine and metabolic disorders of menstrual and reproductive functions. The prevalence rate among girls ranges from 2.2 to 7.5 %, among women of reproductive age – 15 %, and among patients with anovulatory infertility – 73 %. The high prevalence of this pathology in the female population (up to 10 %) places it among the relevant medical problems associated with the development of primary infertility, endometrial hyperplastic processes, obesity, and cardiovascular pathology. The formation of PCOS is often associated with puberty. The instability of gonadotropin synthesis, characteristic of this age period, and the physiological increase in the level of androgens and insulin are precursory factors for the occurrence of PCOS. The article is devoted to the study of factors that can influence the development of the reproductive system and lead to the formation of PCOS. The social, family and perinatal history of girls with emerging polycystic ovary syndrome was studied. It is noted that their puberty is often accompanied by a number of deviations: incorrect order of formation of secondary sexual characteristics, early pubarche, early and late thelarche, early and late menarche. Timely detection of such disorders underlies the formation of a risk group for the development of PCOS and the prevention of reproductive disorders in the future.