USING OF HYALURONIC ACID PREPARATIONS TO STIMULATE REGENERATION WITH TROPHIC DISORDERS AS A RESULT OF CHRONIC VASCULAR DISEASES OF THE LOWER EXTREMITIES
https://doi.org/10.51922/1818-426X.2024.1.42
Abstract
Trophic ulcers as a result of chronic vascular diseases of the lower extremities are an urgent and complex task of surgical treatment. Local treatment of the ulcer is an important role after revascularization. Hyaluronic acid (HA) preparations are among the most promising in this regard. HA provides increased tissue resistance to ischemia, suppression of the inflammatory response, stimulation and acceleration of tissue regeneration. HA ensures the formation of a temporary matrix in a fresh wound, facilitates the diffusion of nutrients and cleans the wound from products of cellular metabolism. Secondly, it takes an active part in the proliferation and migration of keratinocytes, which make up the bulk of the epidermis. Due to the insignificant use of HA in local therapy of trophic disorders of chronic vascular diseases of the lower extremities, it is interesting to further study the effect as part of complex and pathogenetically oriented treatment in patients of this group.
About the Authors
N. A. Rogovoy
УО «Белорусский государственный медицинский университет»
Russian Federation
Russian Federation
S. A. Alekseev
УО «Белорусский государственный медицинский университет»
Russian Federation
Russian Federation
D. V. Kress
УЗ «4-я городская клиническая больница им. Н. Е.Савченко»
Russian Federation
Russian Federation
S. S. Kalinin
УЗ «4-я городская клиническая больница им. Н. Е.Савченко»
Russian Federation
Russian Federation
U. A. Shitikova
УЗ «4-я городская клиническая больница им. Н. Е.Савченко»
Russian Federation
Russian Federation
A. V. Ludchik
ПФ «ГиалСин Технолоджи»
Belarus
Belarus
D. S. Alekseev
УО «Белорусский государственный медицинский университет»
Russian Federation
Russian Federation
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Review
For citations:
Rogovoy N.A., Alekseev S.A., Kress D.V., Kalinin S.S., Shitikova U.A., Ludchik A.V., Alekseev D.S. USING OF HYALURONIC ACID PREPARATIONS TO STIMULATE REGENERATION WITH TROPHIC DISORDERS AS A RESULT OF CHRONIC VASCULAR DISEASES OF THE LOWER EXTREMITIES. Medical Journal. 2024;(1):42-48. (In Russ.) https://doi.org/10.51922/1818-426X.2024.1.42
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