Role of β- and γ-herpesviruses in the development of infectious mononucleosis in children
https://doi.org/10.51922/1818-426X.2022.1.61
Abstract
The purpose of the work is to assess the participation of β- and γ-herpes viruses in the development of infectious mononucleosis in children. The study observed 47 children aged from 10 months to 10 years. Determination of the genome of herpes viruses was carried out by the method of quantitative polymerase chain reaction in “real time”. According to our data, the causes of infectious mononucleosis in children are Epstein-Barr virus (EBV) in 21.4 % of cases, human herpesvirus 6B (HHV-6B) – in 15 % of cases as monoinfection or in combination with EBV and/or human herpes virus type 7 (HHV-7). HHV-7 monoinfection, as well as cytomegalovirus (CMV) as a cause of infectious mononucleosis, was not recorded in our study. In 14.3 % of children, HHV-6B can manifest itself as an acute respiratory disease. The HHV-6B strain of the virus is predominantly circulating in our region.
About the Authors
E. V. Divakova
УО «Белорусский государственный медицинский университет»
Belarus
Belarus
A. P. Kudin
УЗ «Городская детская инфекционная клиническая больница»
Belarus
Belarus
E. P. Kishkurno
ГУО «Белорусская медицинская академия последипломного образования»
Belarus
Belarus
T. V. Amvrosieva
ГУ «Республиканский научно-практический центр эпидемиологии и микробиологии»
Belarus
Belarus
Yu. A. Shilova
ГУ «Республиканский научно-практический центр эпидемиологии и микробиологии»
Belarus
Belarus
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Review
For citations:
Divakova E.V., Kudin A.P., Kishkurno E.P., Amvrosieva T.V., Shilova Yu.A. Role of β- and γ-herpesviruses in the development of infectious mononucleosis in children. Medical Journal. 2022;(1):61-68. (In Russ.) https://doi.org/10.51922/1818-426X.2022.1.61
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