Features of laboratory parameters in patients with pneumonia caused by COVID-19 infection

The article presents the results of a study of changes in the indicators of general, biochemical blood tests and individual coagulogram parameters in patients with COVID-19 pneumonia who were in hospital. The authors found that patients with COVID-19 pneumonia had leukopenia, accelerated ESR, thrombocytopenia, lymphopenia, neutrophilia, which were more often observed in patients with lesions of 25 % or more of lung tissue. Leukocytosis was only in 3 (3.7 %) patients and only in severe lung damage. An increase in the plasma level of D-dimer, fibrinogen, procalcitonin, lactate dehydrogenase, an increase in the value of the prothrombin index, a decrease in the level of plasma albumin was detected only with a lesion of 50 % or more of lung tissue. There was also an increase in the plasma levels of creatinine, alanine aminotransferase, aspartate aminotransferase, creatine phosphokinase, and C-reactive protein in the examined patients. The possibility of risk stratification and assessment of the need for hospitalization of patients with COVID-19 pneumonia, determination of the severity of the course of viral interstitial SARS-CoV-2 pneumonia, evaluation of the effectiveness of prescribed therapy and its correction using laboratory predictors is relevant, among other things, to reduce the risk of post-infectious complications, prevention of possible death.

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