Using blood proteins – traditional tumor markers in diagnosis and prognosis of disease recurrence in non-small cell lung cancer
https://doi.org/10.51922/1818-426X.2026.2.25
Abstract
Objective. To analyze data on the use of blood proteins, traditional cancer markers, in the diagnosis and prediction of disease recurrence in non–small cell lung cancer.
Results. The r eviews ummarizes literature data on the u se of tumor-associated b lood proteins CYFRA 21-1 (cytokeratin fragment 19), SCC (squamous cell carcinoma antigen), NSE (neuron-specific enolase), REA (cancer embryonic antigen), PKM2 (pyruvate kinase M2) and ProGRP (progastrin releasing peptide) as biomarkers for diagnosis and prognosis the return of the disease in non-small cell lung cancer.
Conclusions. Traditional cancer markers are not very effective in diagnosing and predicting the return of the disease in non-small cell lung cancer.
About the Authors
A. D. TaganovichBelarus
Minsk
N. N. Kovganko
Belarus
Minsk
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Review
For citations:
Taganovich A.D., Kovganko N.N. Using blood proteins – traditional tumor markers in diagnosis and prognosis of disease recurrence in non-small cell lung cancer. Medical Journal. 2026;(2):25-34. (In Russ.) https://doi.org/10.51922/1818-426X.2026.2.25
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