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Using blood proteins – traditional tumor markers in diagnosis and prognosis of disease recurrence in non-small cell lung cancer

https://doi.org/10.51922/1818-426X.2026.2.25

Abstract

Objective. To analyze data on the use of blood proteins, traditional cancer markers, in the diagnosis and prediction of disease recurrence in non–small cell lung cancer.

Results. The r eviews ummarizes literature data on the u se of tumor-associated b lood proteins CYFRA 21-1 (cytokeratin fragment 19), SCC (squamous cell carcinoma antigen), NSE (neuron-specific enolase), REA (cancer embryonic antigen), PKM2 (pyruvate kinase M2) and ProGRP (progastrin releasing peptide) as biomarkers for diagnosis and prognosis the return of the disease in non-small cell lung cancer.

Conclusions. Traditional cancer markers are not very effective in diagnosing and predicting the return of the disease in non-small cell lung cancer.

About the Authors

A. D. Taganovich
Belarusian State Medical University
Belarus

Minsk



N. N. Kovganko
Belarusian State Medical University
Belarus

Minsk



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Taganovich A.D., Kovganko N.N. Using blood proteins – traditional tumor markers in diagnosis and prognosis of disease recurrence in non-small cell lung cancer. Medical Journal. 2026;(2):25-34. (In Russ.) https://doi.org/10.51922/1818-426X.2026.2.25

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