medjournalМедицинский журналMedical Journal1818-426XБелорусский государственный медицинский университет10.51922/1818-426X.2026.2.25medjournal-421Research ArticleОБЗОРЫREVIEWSИспользование белков крови – традиционных онкомаркеров в диагностике и прогнозировании возврата заболевания при немелкоклеточном раке легкогоUsing blood proteins – traditional tumor markers in diagnosis and prognosis of disease recurrence in non-small cell lung cancerТагановичА. Д.TaganovichA. D.

Минск

Minsk

КовганкоН. Н.KovgankoN. N.

Минск

Minsk

УО «Белорусский государственный медицинский университет»Belarusian State Medical University202623052026022534Copyright © Таганович А.Д., Ковганко Н.Н., 20262026Таганович А.Д., Ковганко Н.Н.Taganovich A.D., Kovganko N.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://medjournal.ejournal.by/jour/article/view/421Цель

Цель. Проанализировать данные об использовании белков крови – традиционных онкомаркеров в диагностике и прогнозировании возврата заболевания при немелкоклеточном раке легкого.

Результаты

Результаты. В обзоре обобщены данные литературных источников об использовании опухолеассоциированных белков крови CYFRA 21-1 (фрагмент цитокератина 19), SCC (антиген плоскоклеточной карциномы), NSE (нейрон-специфическая енолаза), РЭА (раковый эмбриональный антиген), ПКM2 (пируваткиназа М2) и ProGRP (пептид, высвобождающий прогастрин) в качестве биомаркеров диагностики и прогнозировании возврата заболевания при немелкоклеточном раке легкого.

Выводы

Выводы. Традиционные онкомаркеры обладают невысокой эффективностью в диагностике и прогнозировании возврата заболевания при немелкоклеточном раке легкого.

Objective

Objective. To analyze data on the use of blood proteins, traditional cancer markers, in the diagnosis and prediction of disease recurrence in non–small cell lung cancer.

Results

Results. The r eviews ummarizes literature data on the u se of tumor-associated b lood proteins CYFRA 21-1 (cytokeratin fragment 19), SCC (squamous cell carcinoma antigen), NSE (neuron-specific enolase), REA (cancer embryonic antigen), PKM2 (pyruvate kinase M2) and ProGRP (progastrin releasing peptide) as biomarkers for diagnosis and prognosis the return of the disease in non-small cell lung cancer.

Conclusions

Conclusions. Traditional cancer markers are not very effective in diagnosing and predicting the return of the disease in non-small cell lung cancer.

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The authors declare that there are no conflicts of interest present.