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CORTICAL FOCAL HEMOSIDEROSIS: DESCRIPTION OF TWO CLINICAL CASES

https://doi.org/10.51922/1818-426X.2025.1.130

Abstract

Cortical focal hemosiderosis (CFS) is the deposition of iron metabolites, especially hemosiderin,  in  the  superficial  layers  of  the  brain  and/or  spinal  cord.  Clinical  manifestations in this disease depend on the location of the lesion, however, the deposition of hemosiderin may occur unnoticed. Common symptoms include hearing loss, cerebellar ataxia, pyramidal signs, dementia, urinary incontinence, disorders of the cranial nerves, sensory deficits.

Defects in the dura mater of the spinal cord, intracranial neoplasms, vascular abnormalities, related neurosurgical interventions, cerebral amyloid angiopathy (CAA) can lead to the development of CFS. There is also idiopathic superficial siderosis.

While CFS is diagnosed, it is important to search for the causes of hemosiderosis to increase the quality of life and decrease mortality rates in the structure of patients. For example, CFS is one of the key criteria for the diagnosis of CAA. This type of angiopathy is closely associated with an increased risk of spontaneous intracerebral hemorrhages.

The article presents data on the clinical picture, diagnostic features, as well as the results of our own observation of two clinical cases of CFS.

About the Authors

V. G. Zabrodzets
УО «Белорусский государственный медицинский университет»
Belarus


A. G. Baida
УО «Белорусский государственный медицинский университет»
Belarus


A. P. Leonchyk
ГУ «МНПЦ хирургии, трансплантологии и гематологии»
Belarus


References

1. Klocheva, E. G., Goldobin V. V., Timonina O. I. Magnitno-rezonansnaya tomografiya v diagnostike idiopaticheskogo poverhnostnogo sideroza central’noj nervnoj sistemy // Luchevaya diagnostika i terapiya. – 2015. – № 3. – Р. 96–100.

2. Kulesh, A. A., Gorst N. X., Drobaha V. E., Kajleva N. A., Shestakov V. V. Korkovyj poverh-nostnyj sideroz – novyj MRT-fenomen v nevrologicheskoj praktike: klinicheskie nablyudeniya i obzor literatury // Permskij medicinskij zhurnal. – 2018. – № 5. URL: https://cyberleninka.ru/article/n/korkovyy-poverhnostnyy-sideroz-novyy-mrt-fenomenv-nevrologicheskoy-praktike-klinicheskie-nablyudeniya-iobzor-literatury.

3. Kulesh, A. A., Drobaha V. E., Shestakov V. V. Gemorragicheskie proyavleniya cerebral’noj amiloidnoj angiopatii – ot patogeneza k klinicheskomu znacheniyu // Nevrologiya, nejropsihiatriya, psihosomatika. – 2018. – № 3. URL: https://cyberleninka.ru/article/n/gemorragicheskieproyavleniya-tserebralnoy-amiloidnoy-angiopatii-otpatogeneza-k-klinicheskomu-znacheniyu.

4. Rushkevich, Yu. N. Poverhnostnyj sideroz central’noj nervnoj sistemy: sovremennye predstavleniya, sobstvennye klinicheskie nablyudeniya / Yu. N. Rushkevich, A. V. Astapenko, T. S. Pavlovskaya, V. A. Smeyanovich // Nevrologiya i nejrohirurgiya. Vostochnaya Evropa: mezhdunarodnyj nauchno-prakticheskij zhurnal. – 2023. – T. 13, № 4. – S. 483–496. – Bibliogr. v konce st. UDK 616.831.

5. Suslin, A. S., Kremneva E. I., Krotenkova I. A., Dreval’ M. V., Konovalov R. N., Sergeeva A. N., Arestov S. O., Gerasimova E. V., Gushcha A. O., Krotenkova M. V. Sluchaj poverhnostnogo sideroza central’noj nervnoj sistemy // REJR. – 2018. – № 8(4). – Р. 242–247. doi: 10.21569/2222-7415-2018-8-4-242-247.

6. Greenberg, S. M., Charidimou A. Diagnosis of Cerebral Amyloid Angiopathy: Evolution of the Boston Criteria // Stroke. – 2018. – № 49(2). – Р. 491–497. https://doi.org/10.1161/STROKEAHA.117.016990

7. Storti, B., Canavero I., Gabriel M. M., Capozza A., Rifino N., Stanziano M., Tagliabue L., Bersano A. Iatrogenic cerebral amyloid angiopathy: An illustrative case of a newly introduced disease // Eur J Neurol. – 2023. – № 30(10). – Р. 3397–3399. doi: 10.1111/ene.15997. Epub 2023 Aug 8. PMID: 37494007.


Review

For citations:


Zabrodzets V.G., Baida A.G., Leonchyk A.P. CORTICAL FOCAL HEMOSIDEROSIS: DESCRIPTION OF TWO CLINICAL CASES. Medical Journal. 2025;(1):130-134. (In Russ.) https://doi.org/10.51922/1818-426X.2025.1.130

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ISSN 1818-426X (Print)