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ASSESSMENTS OF 24-HOUR PH-IMPEDANCE ANALYSIS IN PATIENTS WITH HEARBURN

https://doi.org/10.51922/1818-426X.2025.1.119

Abstract

Total of 126 patients with heartburn but without esophageal mucosal injury were studied. They received a standard dose of PPI for 8 and more weeks. All of them underwent 24-hour multichannel intraluminal impedance–pH monitoring without acid suppressive therapy. According to all instrumental studies, three groups were identified: patients with non-erosive reflux disease, functional heartburn and reflux hypersensitivity. Based on the studies the differences between patients with heartburn in these groups were in esophageal acid exposure time, number of total acid/ weakly acidic reflux episodes, correlation between symptoms and reflux events, esophageal clearance function, mucosal integrity values.

About the Authors

I. A. Shalamitskaya-Hulevich
УО «Белорусский государственный медицинский университет»
Belarus


M. V. Kapralov
УО «Белорусский государственный медицинский университет»
Belarus


A. R. Rock
ГУ «Минский научно-практический центр хирургии, трансплантологии и гематологии»
Belarus


V. I. Kurchenkova
УО «Белорусский государственный медицинский университет»
Belarus


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Review

For citations:


Shalamitskaya-Hulevich I.A., Kapralov M.V., Rock A.R., Kurchenkova V.I. ASSESSMENTS OF 24-HOUR PH-IMPEDANCE ANALYSIS IN PATIENTS WITH HEARBURN. Medical Journal. 2025;(1):119-123. (In Russ.) https://doi.org/10.51922/1818-426X.2025.1.119

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ISSN 1818-426X (Print)