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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medjournal</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1818-426X</issn><publisher><publisher-name>Белорусский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51922/1818-426X.2025.1.119</article-id><article-id custom-type="elpub" pub-id-type="custom">medjournal-319</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ НАУЧНЫЕ ПУБЛИКАЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL SCIENTIFIC PUBLICATIONS</subject></subj-group></article-categories><title-group><article-title>Оценка показателей суточной внутрипищеводной рН-имепедансометрии у пациентов с изжогой</article-title><trans-title-group xml:lang="en"><trans-title>ASSESSMENTS OF 24-HOUR PH-IMPEDANCE ANALYSIS IN PATIENTS WITH HEARBURN</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шоломицкая-Гулевич</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shalamitskaya-Hulevich</surname><given-names>I. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Капралов</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kapralov</surname><given-names>M. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рок</surname><given-names>А. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Rock</surname><given-names>A. R.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Курченкова</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kurchenkova</surname><given-names>V. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>УО «Белорусский государственный медицинский университет»</institution><country>Belarus</country></aff><aff xml:lang="ru" id="aff-2"><institution>ГУ «Минский научно-практический центр хирургии, трансплантологии и гематологии»</institution><country>Belarus</country></aff><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>24</day><month>06</month><year>2025</year></pub-date><volume>0</volume><issue>1</issue><fpage>119</fpage><lpage>123</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шоломицкая-Гулевич И.А., Капралов Н.В., Рок А.Р., Курченкова В.И., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Шоломицкая-Гулевич И.А., Капралов Н.В., Рок А.Р., Курченкова В.И.</copyright-holder><copyright-holder xml:lang="en">Shalamitskaya-Hulevich I.A., Kapralov M.V., Rock A.R., Kurchenkova V.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medjournal.ejournal.by/jour/article/view/319">https://medjournal.ejournal.by/jour/article/view/319</self-uri><abstract><p>Проведен анализ исследований 126 пациентов с жалобой на изжогу при терапии стандартной дозой ИПП в течение 8 и более недель с отсутствием изменений слизистой оболочки пищевода, которым была выполнена суточная внутрипищеводная рН-импедансометрия без кислотосупрессивной терапии. По данным инструментальных исследований были выделены три группы: пациенты с неэрозивной рефлюксной болезнью, функциональной изжогой и рефлюксной гиперсенситивностью. Обнаружено, что больные с изжогой отличаются по времени воздействия соляной кислоты на пищевод, количеством гастроэзофагеальных рефлюксов, степени нарушения перистальтики и клиренса пищевода.</p></abstract><trans-abstract xml:lang="en"><p>Total of 126 patients with heartburn but without esophageal mucosal injury were studied. They received a standard dose of PPI for 8 and more weeks. All of them underwent 24-hour multichannel intraluminal impedance–pH monitoring without acid suppressive therapy. According to all instrumental studies, three groups were identified: patients with non-erosive reflux disease, functional heartburn and reflux hypersensitivity. Based on the studies the differences between patients with heartburn in these groups were in esophageal acid exposure time, number of total acid/ weakly acidic reflux episodes, correlation between symptoms and reflux events, esophageal clearance function, mucosal integrity values.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>неэрозивная гастроэзофагеальная рефлюксная болезнь</kwd><kwd>функциональная изжога</kwd><kwd>рефлюксная  гиперсенситивность</kwd><kwd>суточная  внутрипищеводная рН-импедансометрия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>non-erosive gastroesophageal reflux disease</kwd><kwd>functional heartburn</kwd><kwd>reflux hypersensitivity</kwd><kwd>24-hour multichannel intraluminal impedance–pH monitoring</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Пиманов, С. И. 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