FEATURES OF PHYSIOLOGICAL ANEMIA IN EARLY CHILDREN
https://doi.org/10.51922/1818-426X.2025.1.92
Abstract
It is relevant to determine the characteristic parameters of physiological anemia in young children, which does not require correction. Differential diagnosis based on these parameters will identify pathological cases of anemia that require adequate correction. Pathological variants of anemia during this period are associated both with the pathology of pregnancy and childbirth, and with diseases in the postpartum period. Then the iron deficiency state is revealed, as well as the effect on erythropoiesis of various diseases – anemia of chronic diseases – ACD, etc., requiring multidirectional correction.
Purpose of the study: to establish the features (patterns) of physiological anemia in young children in order to identify cases of pathology that “fall out” from this group.
The results of a survey of 526 patients, aged from 4 days to 8 months, who were treated and examined in departments of various profiles of the 3rd State Children’s Clinical Hospital in Minsk in 2021–2023 (in the early childhood departments and the rehabilitation department) were analyzed. The following indicators were studied: erythrocyte content, hemoglobin, color index, MCV, MCH, reticulocytes, reticulocyte hemoglobin, serum iron, serum ferritin. C-reactive protein.
About the Authors
E. V. PetrovaBelarus
V. A. Kuvshinnikov
Belarus
A. F. Ezersky
Belarus
L. V. Novikova
Belarus
S. G. Shenets
Belarus
A. A. Lozitskay
Belarus
References
1. Balashova, E. A. Hemoglobin content in reticulocytes in the diagnosis of absolute iron deficiency in chronic kidney disease in children [Electronic resource], Modern problems of science and education. – 2020. – № 1. Access mode: http://www.science-education.ru/article/View?id=29468.
2. Klimov, L. Ya., Zhetishev R. A., Ivenskaya T. A. et al. Pathogenetic aspects of the formation of anemia in children with celiac disease // J. Pediatrics named after. G. N. Speransky. – 2022. – Vol. 101, № 6. – P. 116–125.
3. Lozitskaya, A. A., Kouvshinnikov V. A., Shenez S. G., Novikova L. V. The advantages of determining the hemoglobin content in reticulocytes for the diagnosis of iron deficiency anemia and latent iron deficiency compared with the determination of ferritin in serum in children // Advances in medicina and medical science: collection of Belarusian State Medical University. – Minsk, 2023. – Vol. 1. – P. 136–140.
4. Machneva, E. B., Zakharova I. N., Tarasova I. S. et al. The average hemoglobin content in reticulocytes is an accurate indicator of iron deficiency in adolescents // Pediatrics. Journal named after G. N. Speransky. – 2015. – Vol. 94, № 6. – P. 33–38.
5. Nikitina, I. L. Childhood diseases. – Saint Petersburg: Special Lit., 2022. – Vol. 2. – P. 354–369.
6. Pshenichnaya, K. I., Jelenina L. A., Kasatkina T. M., Ivashikina T. M., Zaidina M. V. Indicator of reticulocyte hemoglobin in diagnostics of fe-deficiency in children // Pediatrician. – 2018. – Vol. 9, № 6. – Р. 73–76.
7. Rumyantsev, A. G., Kartelishev A. V. Guidelines for local and family physicians – pediatricians. – M., 2020. – Vol. 1. – P. 500–511.
8. Lorenz, L. Reticulocyte haemoglobin content as a marker of iron deficiency / L. Lorenz, J. Arand, K. Buchner [et al.] // Arch Dis Child Fetal Neonatal Ed. – 2015. – Vol. 100(3). – P. F198–F202.
Review
For citations:
Petrova E.V., Kuvshinnikov V.A., Ezersky A.F., Novikova L.V., Shenets S.G., Lozitskay A.A. FEATURES OF PHYSIOLOGICAL ANEMIA IN EARLY CHILDREN. Medical Journal. 2025;(1):92-96. (In Russ.) https://doi.org/10.51922/1818-426X.2025.1.92