BLOOD LOSS DURING SURGICAL TREATMENT OF BENIGN PROSTATIC HYPERPLASIA
https://doi.org/10.51922/1818-426X.2025.1.57
Abstract
Objective. To study the frequency of blood transfusions during open adenomectomy and TURP, as well as to evaluate the degree of blood loss and the frequency of red blood cell transfusions in a prospective randomized clinical trial.
Materials and methods. The frequency of open operations and TURP in the 4th Minsk City Clinical Hospital for 2016–2018. The frequency of blood transfusions was studied in a retrospective study, and the degree of blood loss and the frequency of red blood cell transfusions were determined in a prospective randomized clinical trial.
Results. The rate of open adenomectomies was 33.6 %, and TURP – 66.4 %. The rate of red blood cell transfusion after TURP was 2.8 % (21 patients), after open adenomectomy – % (33 patients) (χ2 = 2, p = 0.001)). In a randomized study, the frequency of blood transfusions in the main group was 2.2 % (2 patients), in the comparison group – 12.6 % (11 patients) (F = 0.199, p = 0.007). Total blood loss after adenomectomy from the open approach was 500 (373–600) ml in patients from the comparison group, 240 (124–340) ml in patients from the main group (U = 881.0, p = 0.001).
Conclusion. The frequency of open operations for large volumes of BPH has remained high in recent years – 30.4–42.2 %. The total blood loss after open adenomectomy is 2.1 times lower, and the frequency of blood transfusions is 5.5 times lower with intraoperative use of the Gamastat, which undoubtedly indicates its good hemostatic effect.
About the Authors
V. G. AdashchikBelarus
Yu. T. Buldyk
Belarus
A. N. Korol
Belarus
References
1. EAU Guidelines on Management of Non-Neurogenic Male Lower Urinary Tract Symptoms (LUTS), incl. Benign Prostatic Obstruction (BPO) [Electronic resource] / S. Gravas [et al.]. – 2019. – Mode of access: https://uroweb.org/wp-content/uploads/EAU-Guidelines-on-the-Managementof-Non-Neurogenic-Male-LUTS-2019.pdf. – Date of access: 29.05.2023.
2. Gratzke, C. et al. Complications and early postoperative outcome after open prostatectomy in patients with benign prostatic enlargement: results of a prospective multicenter study // J Urol. – 2007. – Vol. 177. – P. 1419.
3. Holmium laser enucleation of the prostate versus open prostatectomy for prostates > 70 g: 24-month follow-up / R. Naspro [et al.] // Eur. Urol. – 2006. – Vol. 50, № 3. – P. 563–568.
4. Nitkin, D. M. Sostoyanie urologicheskoj sluzhby Respubliki Belarus’ / D. M. Nitkin // III S”ezd OO “Belorusskaya associaciya urologov: sb. nauch. tr. Resp. nauch.- prakt. konf. s mezhdunar. uchastiem, Minsk, 26 okt. 2018 g. – [Opubl. v zhurn.] Recept. – 2018. – Vol. 21, pril. – S. 6–7.
5. Vysokotekhnologichnaya ekstrauretral’naya adenomektomiya / N. F. Sergienko [et al.] // Urologiya. – 2012. – № 5. – S. 58–61.
6. Sravnenie rezul’tatov laparoskopicheskoj i otkrytoj pozadilonnoj adenomektomii / S. V. Kotov [i dr.] // 110 let Rossijskomu obshchestvu urologov: materialy XIII s”ezda, XVII kongr. Ros. o-va urologov, Moskva, 8–10 noyab. 2017 g. – M., 2017. – S. 364.
7. Adashchik, V. G. Metody gemostaza pri otkrytoj adenomektomii / V. G. Adashchik, A. V. Strockij // Medicinskie novosti. – 2018. – № 7. – S. 3–6.
8. Autodonorstvo i autogemotransfuzii: rukovodstvo / A. A. Ragimov [et al.]; pod red. A. A. Ragimova. – M.: GEOTARMedia, 2011. – 256 s.
9. Rebrova, O. Yu. Statisticheskij analiz medicinskih dannyh. Primenenie paketa prikladnyh programm STATISTICA / O. Yu. Rebrova. – M.: Media Sfera, 2002. – 305 s.
10. Mamaev, A. N. Statisticheskie metody v medicine / A. N. Mamaev, D. A. Kudlaj. – M.: Prakt. medicina, 2021. – 135 s.
11. Petri, A. Naglyadnaya medicinskaya statistika: ucheb. posobie: per. s angl. / A. Petri, K. Sebin. – M.: GEOTAR-MED, 2021. – 225 s.
12. Fletcher, R. I. Klinicheskaya epidemiologiya. Osnovy dokazatel’noj mediciny: per. s angl. / R. Fletcher, S. Fletcher, E. Vagner; pod obshch. red. S. E. Bashchinskogo, S. Yu. Varshavskogo. – M.: Media Sfera, 1998. – 352 s.
Review
For citations:
Adashchik V.G., Buldyk Yu.T., Korol A.N. BLOOD LOSS DURING SURGICAL TREATMENT OF BENIGN PROSTATIC HYPERPLASIA. Medical Journal. 2025;(1):57-62. (In Russ.) https://doi.org/10.51922/1818-426X.2025.1.57