Drug ototoxicity, diagnosis, prevention and treatment
https://doi.org/10.51922/1818-426X.2023.3.31
Abstract
Hearing helps a person by warning him of danger, serves to receive information and to acquire knowledge, and can cause very strong emotions. Drug damage to the inner ear occurs during the treatment of other diseases. The main reason is incorrectly selected drugs or non-compliance by patients with the recommended dosage and frequency of administration.
This review defines the concept of “iatrogenic ototoxicity”, describes the mechanisms of its occurrence in some groups of drugs. Also, measures have been proposed to prevent the ototoxic effect of drugs that cause irreversible hearing changes up to deafness or lead to temporary hearing loss and hearing loss when applied topically, especially in the presence of perforation of the tympanic membrane.
There is no specific treatment for drug-induced iatrogenic ototoxicity. The report lists drugs that have ototoxicity, as well as clinical and pharmacological characteristics of drugs used to improve hearing in sensorineural hearing loss.
The review proves that the significant ototoxicity of certain groups of drugs in many cases limits or completely excludes their prescription to patients, and also requires strict medical control, timely detection and accounting.
About the Authors
G. G. Maksimenya
УО «Белорусский государственный медицинский университет»
Belarus
Belarus
A. Ch. Buzel
УО «Белорусский государственный медицинский университет»
Belarus
Belarus
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Review
For citations:
Maksimenya G.G., Buzel A.Ch. Drug ototoxicity, diagnosis, prevention and treatment. Medical Journal. 2023;(3):31-44. (In Russ.) https://doi.org/10.51922/1818-426X.2023.3.31
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