Efficiency of treatment of injury on a model of solid and mosaic burns in animals using a tissue equivalent of the skin
https://doi.org/10.51922/1818-426X.2022.3.24
Abstract
The effectiveness of the treatment of thermal burns in experimental animals using the developed skin tissue equivalent based on cultured skin fibroblasts and keratinocytes (TES) was studied.The terms of wound healing in experimental and control groups of animals with thermal burns IIIABIV degree were studied. An analysis was carried out using morphological methods for studying sections of biopsy specimens of burn wounds of the skin of animals at various periods of healing. The stimulating effect of TES on regenerative processes in wounds was revealed. When using TES in animals with solid and mosaic burns, there was a shortening of the wound healing time by 1.64 times compared with the control group of untreated animals.
About the Authors
A. Ch. Chastoits
ГУО «БелМАПО»
Belarus
Belarus
I. B. Vasilevich
ГНУ «Институт биофизики и клеточной инженерии» НАН Беларуси, Минск, Беларусь
Belarus
Belarus
Z. B. Kvacheva
ГНУ «Институт биофизики и клеточной инженерии» НАН Беларуси, Минск, Беларусь
Belarus
Belarus
A. V. Butenka
ГНУ «Институт биофизики и клеточной инженерии» НАН Беларуси, Минск, Беларусь
Belarus
Belarus
K. A. Matsiyevski
ГНУ «Институт биофизики и клеточной инженерии» НАН Беларуси, Минск, Беларусь
Belarus
Belarus
V. M. Basalai
ГУО «БелМАПО»
Belarus
Belarus
T. Е. Vladimirskaya
ГУО «БелМАПО»
Belarus
Belarus
V. N. Podgaiski
ГУО «БелМАПО»
Belarus
Belarus
I. D. Volotovski
ГНУ «Институт биофизики и клеточной инженерии» НАН Беларуси, Минск, Беларусь
Belarus
Belarus
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Review
For citations:
Chastoits A.Ch., Vasilevich I.B., Kvacheva Z.B., Butenka A.V., Matsiyevski K.A., Basalai V.M., Vladimirskaya T.Е., Podgaiski V.N., Volotovski I.D. Efficiency of treatment of injury on a model of solid and mosaic burns in animals using a tissue equivalent of the skin. Medical Journal. 2022;(3):24-29. (In Russ.) https://doi.org/10.51922/1818-426X.2022.3.24
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