Message. Experience of using platelet-rich plasma in the treatment of patients with extensive wound defects
https://doi.org/10.51922/1818-426X.2023.2.108
Abstract
Allogeneic plasma enriched with platelets (hereinafter ALPEP/PRP) is often used in various branches of medicine. The scope of application of PRP therapy varies from stimulation of bone regeneration, healing of wounds and ulcers, musculoskeletal injuries to increasing the possibilities in the engraftment of various types of transplants. Due to the native properties of platelet-enriched plasma, its introduction into the human body is one of the promising manipulations in tissue regeneration. After the destruction of platelets, ALPEEP contains html5-dom-document-internal-entity2-945-end-granules, from which, after activation, many factors are released, such as transforming growth factor-beta (TGF-html5-dom-document-internal-entity2-946-end), vascular endothelial growth factor (VGFF) and epidermal growth factor (EGF).
About the Authors
D. S. Tratsiak
Государственное учреждение «432 ордена Красной Звезды Главный военный клинический медицинский центр Вооруженных Сил Республики Беларусь»
Belarus
Belarus
A. P. Truchan
Государственное учреждение «432 ордена Красной Звезды Главный военный клинический медицинский центр Вооруженных Сил Республики Беларусь»
Belarus
Belarus
D. V. Vasilyev
Государственное учреждение «432 ордена Красной Звезды Главный военный клинический медицинский центр Вооруженных Сил Республики Беларусь»
Belarus
Belarus
K. A. Fiodarau
Государственное учреждение «432 ордена Красной Звезды Главный военный клинический медицинский центр Вооруженных Сил Республики Беларусь»
Belarus
Belarus
A. D. Vasilyeva
УО «Белорусский государственный медицинский университет»
Belarus
Belarus
References
1. Boldyreva, O. V., Vahrushev S. G., Toropova L. A. Primenenie plazmy, obogashchennoj trombocitami, v medicinskoj praktike // Sovremennye problemy nauki i obrazovaniya. – 2016. – № 5.
2. Bogdan, V. G., Gain Yu. M. et al. Vliyanie obogashchennoj trombocitami plazmy na zhiznesposobnost’, skorost’ rosta, morfofenotipicheskie i sekretornye osobennosti mezenhimal’nyh stromal’nyh kletok zhirovoj tkani cheloveka // Medicinskij zhurnal. – 2011. – № 1. – S. 27–29.
3. Voenno-polevaya hirurgiya: uchebnik / pod red. Prof. I. M. Samohvalova. – Sankt-Peterburg, 2021. – 141 p.
4. Dejkalo, V. P., Mastykov A. N., Boloboshko K. B. Obogashchennaya trombocitami plazma v lechenii zabolevanij i povrezhdenij oporno-dvigatel’nogo apparata // Vestnik VGMU. – 2011. – Vol. 10, № 4. – Р. 6–11.
5. Medvedev, V. L., Kogan M. I., Mihajlov I. V., Lepetunov S. N. Autologichnaya plazma obogashchyonnaya trombocitami: chto eto i dlya chego? // Vestnik urologii. – 2020. – № 8(2). – Р. 67–77.
6. Tavukcu, H. H., Aytaç Ö., Atuğ F., Alev B., Çevik Ö., Bülbül N., Yarat A., Çetinel Ş., Şener G., Kulaksızoğlu H. Protective effect of platelet-rich plasma on urethral injury model of male rats // Neurourol Urodyn. – 2018. – № 37(4). – Р. 1286–1293.
7. Weiser, L., Bhargava M., Attia E., Torzilli P. A. Effect of serum and platelet-derived growth factor on chondrocytes grown in collagen gels // Tissue Eng. – 1999. – № 5(6). – Р. 533–544.
Review
For citations:
Tratsiak D.S., Truchan A.P., Vasilyev D.V., Fiodarau K.A., Vasilyeva A.D. Message. Experience of using platelet-rich plasma in the treatment of patients with extensive wound defects. Medical Journal. 2023;(2):108-112. (In Russ.) https://doi.org/10.51922/1818-426X.2023.2.108
Views:
7
Email this article 