Cytotoxicity of materials used for fixing bracket systems
https://doi.org/10.51922/1818-426X.2024.2.87
Abstract
The article presents the results of a study of the cytotoxic effect of composite materials used to fix braces: Transbond color change adhesive (3M), Heliosit orthodontic (Ivoclar Vivadent), as well as Single bond universal adhesive (3M), on HaCaT keratinocyte cell culture.
The authors revealed significant cytotoxicity of Single Bond Universal (3M) and Transbond plus Color Change adhesive and moderate cytotoxicity of Heliosit Orthodontic on HaCaT keratinocyte cell culture.
According to the results obtained, the authors emphasize the need to provide a number of measures to minimize the negative impact of composites on both the patient and the orthodontist.
About the Authors
T. V. GorlachevaBelarus
K. I. Pavlov
Belarus
T. N. Terekhova
Belarus
References
1. Korenevskaya, N. A. Biosovmestimost kompozicionnyh plombirovochnyh materialov / N. A. Korenevskaya // UO «Vitebskij gosudarstvennyj ordena Druzhby narodov medicinskij universitet», g. Vitebsk, Respublika Belarus // Vestnik VGMU. – 2016. – Vol. 15, № 3. – S. 7–17.
2. Adham, R. M. Genotoxicity and Cytotoxicity of Orthodontic Bonding Adhesives: A Review / R. M. Adham, N. A. Rahman, T. P. Kannan // Sains Malaysiana. – 2019. – Vol. 48(8). – P. 1685–1695.
3. Bisphenol A in infertile patients: impact on assisted reproductive technologies outcomes / A. G. Syrkasheva [et al.] // Int J Environ Res Public Health. – 2019. – Vol. 16(9). – P. 1627.
4. Clinical and Experimental Dental Research Cytotoxicity evaluation of dental and orthodontic light-cured composite resins / R. Bationo [et al.] // Materials (Basel). – 2021. – Vol. 14(18). – P. 5225.
5. Cytotoxic and Genotoxic Effects of Composite Resins on Cultured Human Gingival Fibroblasts / F. De Angelis [et al.] / Materials (Basel). – 2021. – Vol. 14(18). – P. 5225.
6. Cytotoxic and Genotoxic Effects of Composite Resins on Cultured Human Gingival Fibroblasts / F. De Angelis [et al.] // Physiol Res. – 2020. – P. S295–S304.
7. Cytotoxicity evaluation of dental and orthodontic light-cured composite resins / R. Bationo [et al.] // Clin Exp Dent Res. – 2021. – Vol. 7(1). – P. 40–48.
8. Dental Composites – a Low-Dose Source of Bisphenol A? / M. Simkova [et al.]. – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603723/.
9. Genotoxic and cytotoxic potential of methacrylate-based orthodontic adhesives / A. Taubmann [et al.] // Oral Investigations. – 2021. – Vol. 25. – P. 2569–2581.
10. Resin Composites and Dental Sealants Release Bisphenol-A, How Might This Affect Our Clinical Management? – A Systematic Review / A. B. Paula // Int J Environ Res Public Health. – 2019. – Vol. 16(9). – P. 1627.
11. Metod issledovaniya citotoksichnosti himicheskih veshestv in vitro: instrukciya po primeneniyu: utv. M-vom zdravoohr. Resp. Belarus 10.06.2022, reg. № 018-1221 / sost. kand. med. nauk K. I. Pavlov, S. V. Arabej, L. A. Hvatova, A. M. Naborovskaya, L. M. Kundelskaya, G. A. Kurklinskaya, T. G. Metelica, E. V. Chegodaeva, M. A. Matlakova, kand. med. nauk, docent A. V. Gindyuk. – Minsk: Uchrezhdenie obrazovaniya «Belorusskij gosudarstvennyj medicinskij universitet», 2022. – 19 s.
Review
For citations:
Gorlacheva T.V., Pavlov K.I., Terekhova T.N. Cytotoxicity of materials used for fixing bracket systems. Medical Journal. 2024;(2):87-91. (In Russ.) https://doi.org/10.51922/1818-426X.2024.2.87