N-acetyl cysteine: possibilities and prospects for use in urinary tract infections
https://doi.org/10.51922/1818-426X.2024.2.14
Abstract
A review of literature data on the prospects for the use of acetylcysteine in the treatment of urinary tract infections is presented. In addition to the well-known mucolytic effect, ACC has antibacterial, anti-inflammatory and antioxidant properties. A number of studies have revealed the ability of ACC to suppress the development of bacterial biofilms, which is important in the treatment of chronic infections, including urinary tract infections. Studies have also demonstrated the anti-inflammatory activity of ACC, expressed in a decrease in the production of interleukins. Of interest is the property of ACC to suppress urease Proteus mirabilis, one of the main causative agents of nasocomial infection in urology. This property of ACC can be used in the prevention of infections associated with urinary catheters and ureteral stents incrustations.
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Review
For citations:
Gavrusev A.A. N-acetyl cysteine: possibilities and prospects for use in urinary tract infections. Medical Journal. 2024;(2):14-18. (In Russ.) https://doi.org/10.51922/1818-426X.2024.2.14
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