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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medjournal</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1818-426X</issn><publisher><publisher-name>Белорусский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51922/1818-426X.2023.4.4</article-id><article-id custom-type="elpub" pub-id-type="custom">medjournal-3</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Новые подходы в комплексном лечении закрытых сегментарных и многооскольчатых диафизарных переломов костей голени</article-title><trans-title-group xml:lang="en"><trans-title>New approaches in the complex treatment of closed segmental and multi-fragmented diaphyseal fractures of the lower leg bones</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ванькович</surname><given-names>П. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Vankovich</surname><given-names>P. E.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кезля</surname><given-names>О. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Kezlya</surname><given-names>O. P.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Селицкий</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sialitski</surname><given-names>A. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ГУО «Белорусская медицинская академия последипломного образования»</institution><country>Belarus</country></aff><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>17</day><month>06</month><year>2025</year></pub-date><volume>0</volume><issue>4</issue><fpage>4</fpage><lpage>13</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ванькович П.Э., Кезля О.П., Селицкий А.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Ванькович П.Э., Кезля О.П., Селицкий А.В.</copyright-holder><copyright-holder xml:lang="en">Vankovich P.E., Kezlya O.P., Sialitski A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medjournal.ejournal.by/jour/article/view/3">https://medjournal.ejournal.by/jour/article/view/3</self-uri><abstract><p>Проведен анализ мировой и отечественной литературы, посвященной современным подходам к комплексному лечению закрытых сегментарных и многооскольчатых диафизарных переломов костей голени у лиц трудоспособного возраста, а также освящены патогенетические механизмы ремоделирования в зоне перелома. На сегодняшний день отсутствует исчерпывающая информации о необходимом количестве сеансов и их продолжительности при использовании гипербарической оксигенации и антиоксидантов в пред- и послеоперационном периодах у пациентов с переломами костей голени. Это обосновывает актуальность дальнейших исследований с целью разработки новой концепции комплексного лечения, заключающегося в дифференцированном подходе к применению гипербарического терапевтического кислорода в сочетании с антиоксидантами у пациентов с переломами костей голени.</p></abstract><trans-abstract xml:lang="en"><p>The analysis of the world and domestic literature devoted to modern approaches to the complex treatment of closed segmental and multi-fragmented diaphyseal fractures of the lower leg bones in people of working age is carried out, as well as the pathogenetic mechanisms of remodeling in the fracture zone are consecrated. To date, there is no comprehensive information on the required number of sessions and their duration when using hyperbaric oxygenation and antioxidants in the pre- and postoperative periods in patients with fractures of the lower leg bones. This justifies the relevance of further research in order to develop a new concept of complex treatment, which consists in a differentiated approach to the use of hyperbaric therapeutic oxygen in combination with antioxidants in patients with fractures of the lower leg bones.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сегментарные переломы большеберцовой кости</kwd><kwd>комплексное лечение</kwd><kwd>гипербарическая оксигенация</kwd><kwd>репаративная регенерация</kwd><kwd>антиоксидант</kwd></kwd-group><kwd-group xml:lang="en"><kwd>segmental fractures of the tibia</kwd><kwd>complex treatment</kwd><kwd>hyperbaric oxygenation</kwd><kwd>reparative regeneration</kwd><kwd>antioxidant</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ванькович, П. Э., Кезля О. П. 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