References

medjournal

Медицинский журнал

Medical Journal

1818-426X

Белорусский государственный медицинский университет

10.51922/1818-426X.2022.3.30

medjournal-264

Research Article

ОБЗОРЫ И ЛЕКЦИИ

REVIEWS AND LECTURES

Эпидемиологические аспекты новой коронавирусной инфекции COVID-19

Epidemiological aspects of the new coronavirus infection COVID-19

Чистенко

Г. Н.

Chistenko

G. N.

Вальчук

И. Н.

Valchuk

I. N.

Федорова

И. В.

Fedorova

I. V.

Бандацкая

М. И.

Bandatskaya

M. I.

УО «Белорусский государственный медицинский университет»Belarus

2022

22062025

033038

2025

Чистенко Г.Н., Вальчук И.Н., Федорова И.В., Бандацкая М.И.

Chistenko G.N., Valchuk I.N., Fedorova I.V., Bandatskaya M.I.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://medjournal.ejournal.by/jour/article/view/264

В статье представлены наиболее существенные эпидемиологические черты пандемии новой коронавирусной инфекции. Указаны механизмы проникновения SARSCoV2 в организм, пути и факторы передачи, иммунологические механизмы взаимодействия вируса с клеточнорецепторным аппаратом. Рассмотрены вопросы формирования популяционного иммунитета к COVID19 посредством специфической профилактики: современные биоплатформы вакцин и их сравнительные характеристики, профиль безопасности, вопросы иммунологической и эпидемиологической эффективности вакцинации в условиях непрерывного появления вариантов SARSCoV2, вызывающих озабоченность. Изложены прогнозируемые эпидемиологические модели развития пандемии. Раскрыты основные направления комплексной системы профилактики новой коронавирусной инфекции в Беларуси.

The most significant epidemiological features of the pandemic with a new coronavirus infection are presented in the article. The mechanisms of penetration of SARSCoV2 into the body, ways and factors of transmission, immunological mechanisms of interaction of the virus with the cellular receptor apparatus are indicated. The issues of the formation of population immunity to COVID19 through specific prevention are considered. Modern biological platforms of vaccines and their comparative characteristics, safety profile, immunological and epidemiological effectiveness of vaccination in the conditions of continuous emergence of SARSCoV2 variants of concern are discussed. The predicted epidemiological models of the pandemic development and the main directions of the complex system of prevention of coronavirus infection in Belarus are presented.

пандемия COVID-19эпидемиологический прогнозустойчивость SARS-CoV-2эволюция вирусоввакциныспецифическая профилактикапопуляционный иммунитет

COVID-19 pandemicepidemiological prognosisSARS-CoV-2 resistancevirus evolutionvaccinesspecific preventionpopulation immunity

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The authors declare that there are no conflicts of interest present.